1382 PULMONARY VASCULAR PATHOLOGY IN FATAL NEONATAL MECONIUM ASPIRATION

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Pulmonary function in children after neonatal meconium aspiration syndrome

Eighteen children aged 6 to 11 years old who fulfilled criteria for the diagnosis of neonatal meconium aspiration syndrome were investigated to find out the prevalence of previous and current respiratory symptoms, and abnormal pulmonary function tests, chest radiographs, and ventilation scans. Eleven of the 18 had no respiratory symptoms and eight of these had normal pulmonary function on testi...

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[Pulmonary function in children after neonatal meconium aspiration syndrome].

BACKGROUND Meconium aspiration syndrome is a disease of the newborn mature or post mature. The acute pulmonary consequences can be extremely severe. In the few studies of the long-term pulmonary sequelae, it seems that certain children surviving meconium aspiration syndrome keep an obstructive syndrome. The aim of our study was to assess long term respiratory residual damage from meconium aspir...

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Meconium aspiration syndrome in neonates

Perhaps the most significant changes in airway management over the recent years have been in the management of an infant delivered through meconium- stained amniotic fluid( MSAF). MSAF occurs in approximately 10℅ to 20℅ of all deliveries and increases to over 30℅ in deliveries after 42 weeks gestation. Meconium aspiration syndrome ( MAS) occurs in about 2℅ to 5℅ of these cases with a high morta...

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Meconium Aspiration

The decrease in the incidence of MAS in the period of a decade has been attributed to the reduction in post-term delivery, aggressive management of abnormal heart rate monitoring, and decreased number of infants with a low Apgar score. [4]Elective induction of labour for pregnancies at or beyond 41 weeks has been shown to be associated with significant reduction in the incidence of MAS and fewe...

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Role of Meconium and Hypoxia in Meconium Aspiration-Induced Lung Injury in Neonatal Rabbits

BACKGROUND We previously showed that meconium causes lung cell death by apoptosis and inflammatory cytokine expression. Whether this is due to meconium exposure itself, or meconium related hypoxia remains unclear. OBJECTIVES To elucidate the effects of meconium, saline, milk, hypoxia and hyperoxia induced lung injury. DESIGN/METHODS We studied 5 groups of rabbit pups: (I) normal saline; (II...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1981

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198104001-01411